Sterile Rubber Stopper D4 20mm

The 20mm Sterile Lyophilization Rubber Stopper (Model 20-D4) from vialshop.com delivers precise, high-performance sealing for pharmaceutical, diagnostic, and research applications requiring freeze-drying (lyophilization). Manufactured from medical-grade bromobutyl/chlorobutyl rubber under strict ISO standards, this stopper provides superior chemical stability, ultra-low extractables, and exceptional resealability.

Its three-leg (vented) design enables seamless vapor escape during the sublimation phase of freeze-drying. Once pressed down in vacuum conditions, it creates a fully airtight, hermetic seal that protects sensitive active ingredients, biologicals, and injectable powders from oxygen, humidity, and atmospheric contamination.

Key Features

• Specialized Lyophilization Design (20-D4): Vented multi-leg configuration allows efficient moisture sublimation during freeze-drying before full mechanical seating.

• Pharmaceutical-Grade Butyl Rubber: High-purity bromobutyl/chlorobutyl formulation ensures minimal drug interaction, low gas permeability, and zero leachables.

• Pre-Sterilized & Ready to Use: Processed to meet rigorous cleanroom and sterility standards (YBB / EP compliance) for sensitive pharmaceutical workflows.

• Standard 20mm Neck Compatibility: Fits seamlessly onto standard 20mm finish tubular and molded glass injection vials, serum bottles, and antibiotic vials.

• High Thermal & Vacuum Integrity: Maintains physical elasticity and airtight performance across extreme temperature shifts during freeze-drying cycles.

Technical Specifications

Common Applications

• Lyophilized (Freeze-Dried) Pharmaceuticals: Secures freeze-dried powders, biologicals, proteins, and antibiotic formulations.

• Injectable Drug Packaging: Ideal for high-purity pharmaceutical production requiring crimp-cap aluminum sealing.

• Diagnostic & Reagent Storage: Protects sensitive laboratory reference standards and diagnostic reagents from moisture degradation.